Association Between Gestational Diabetes and Incident Maternal CKD: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

ABSTRACT:

Background

Gestational diabetes mellitus (GDM) is associated with increased risk for diabetes mellitus, metabolic syndrome, and cardiovascular disease. We evaluated whether GDM is associated with incident chronic kidney disease (CKD), controlling for prepregnancy risk factors for both conditions.

Study design

Prospective cohort.

Setting & participants

Of 2,747 women (aged 18-30 years) enrolled in the Coronary Artery Risk Development in Young Adults (CARDIA) Study in 1985 to 86, we studied 820 who were nulliparous at enrollment, delivered at least 1 pregnancy longer than 20 weeks' gestation, and had kidney function measurements during 25 years of follow-up.

Predictor

GDM was self-reported by women for each pregnancy.

Outcomes

CKD was defined as the develo

SUBMITTER: Dehmer EW 

PROVIDER: S-EPMC5742081 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature