Comparative Ecology of Capsular Exophiala Species Causing Disseminated Infection in Humans.

ABSTRACT: Exophiala spinifera and Exophiala dermatitidis (Fungi: Chaetothyriales) are black yeast agents potentially causing disseminated infection in apparently healthy humans. They are the only Exophiala species producing extracellular polysaccharides around yeast cells. In order to gain understanding of eventual differences in intrinsic virulence of the species, their clinical profiles were compared and found to be different, suggesting pathogenic strategies rather than coincidental opportunism. Ecologically relevant factors were compared in a model set of strains of both species, and significant differences were found in clinical and environmental preferences, but virulence, tested in Galleria mellonella larvae, yielded nearly identical results. Virulence facto

SUBMITTER: Song Y 

PROVIDER: S-EPMC5742258 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature