Ontology highlight
ABSTRACT:
SUBMITTER: Rios-Arce ND
PROVIDER: S-EPMC5742533 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Advances in experimental medicine and biology 20170101
The intestinal epithelial barrier plays an essential role in maintaining host homeostasis. The barrier regulates nutrient absorption as well as prevents the invasion of pathogenic bacteria in the host. It is composed of epithelial cells, tight junctions, and a mucus layer. Several factors, such as cytokines, diet, and diseases, can affect this barrier. These factors have been shown to increase intestinal permeability, inflammation, and translocation of pathogenic bacteria. In addition, dysregula ...[more]