Impulsivity in unaffected adolescent biological relatives of schizophrenia patients.

ABSTRACT: OBJECTIVE:Although schizophrenia is not a prototypic impulse-control disorder, patients report more impulsive behaviors, have higher rates of substance use, and show dysfunction in brain circuits that underlie impulsivity. We investigate impulsivity in unaffected biological relatives of schizophrenia patients to further understand the relationships between schizophrenia risk and impulse control during adolescence. METHOD:Group differences in impulsivity (UPPS-P Impulsive Behavior Scale and delay discounting) were tested in 210 adolescents contrasting 39 first- and 53 second-degree biological relatives of schizophrenia patients, and 118 subjects with no schizophrenia family history (NSFH). RESULTS:Compared to NSFH adolescents and to second-degree relatives, first-degree relatives of schizop

SUBMITTER: Ho BC 

PROVIDER: S-EPMC5742548 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature