Unknown

Dataset Information

0

Three New Malyngamides from the Marine Cyanobacterium Moorea producens.

ABSTRACT: Three new compounds of the malyngamide series, 6,8-di-O-acetylmalyngamide 2 (1), 6-O-acetylmalyngamide 2 (2), and N-demethyl-isomalyngamide I (3), were isolated from the marine cyanobacterium Moorea producens. Their structures were determined by spectroscopic analysis and chemical derivatization and degradation. These compounds stimulated glucose uptake in cultured L6 myotubes. In particular, 6,8-di-O-acetylmalyngamide 2 (1) showed potent activity and activated adenosine monophosphate-activated protein kinase (AMPK).

SUBMITTER: Sueyoshi K 

PROVIDER: S-EPMC5742827 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Three New Malyngamides from the Marine Cyanobacterium Moorea producens.

Sueyoshi Kosuke K   Yamano Aki A   Ozaki Kaori K   Sumimoto Shimpei S   Iwasaki Arihiro A   Suenaga Kiyotake K   Teruya Toshiaki T  

Marine drugs 20171129 12

Three new compounds of the malyngamide series, 6,8-di-<i>O</i>-acetylmalyngamide 2 (<b>1</b>), 6-<i>O</i>-acetylmalyngamide 2 (<b>2</b>), and <i>N</i>-demethyl-isomalyngamide I (<b>3</b>), were isolated from the marine cyanobacterium <i>Moorea producens</i>. Their structures were determined by spectroscopic analysis and chemical derivatization and degradation. These compounds stimulated glucose uptake in cultured L6 myotubes. In particular, 6,8-di-<i>O</i>-acetylmalyngamide 2 (<b>1</b>) showed p  ...[more]

Similar Datasets

Unknown Two new lyngbyatoxin derivatives from the Cyanobacterium, Moorea producens.
| S-EPMC4278201 | biostudies-literature
Unknown A new lyngbyatoxin from the Hawaiian cyanobacterium Moorea producens.
| S-EPMC4052313 | biostudies-literature
Unknown UV Resistance of bacteria from the Kenyan Marine cyanobacterium Moorea producens.
| S-EPMC6460272 | biostudies-literature
Unknown New Cerebroside and Nucleoside Derivatives from a Red Sea Strain of the Marine Cyanobacterium Moorea producens.
| S-EPMC6272925 | biostudies-literature
Unknown Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens.
| S-EPMC3962764 | biostudies-literature
Unknown Antimalarial Peptide and Polyketide Natural Products from the Fijian Marine Cyanobacterium Moorea producens.
| S-EPMC7142784 | biostudies-literature
Unknown Neo-Aplysiatoxin A Isolated from Okinawan Cyanobacterium Moorea Producens.
| S-EPMC7037229 | biostudies-literature
Unknown Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows.
| S-EPMC4519256 | biostudies-literature
Unknown A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens.
| S-EPMC5748289 | biostudies-literature
Unknown A novel uncultured heterotrophic bacterial associate of the cyanobacterium Moorea producens JHB.
| S-EPMC5006271 | biostudies-literature