Individual and Joint Effects of Early-Life Ambient Exposure and Maternal Prepregnancy Obesity on Childhood Overweight or Obesity.

ABSTRACT:

Background

Although previous studies suggest that exposure to traffic-related pollution during childhood increases the risk of childhood overweight or obesity (COWO), the role of early life exposure to fine particulate matter (aerodynamic diameter <2.5 μm; PM_2.5) and its joint effect with the mother’s prepregnancy body mass index (MPBMI) on COWO remain unclear.

Objectives

The present study was conducted to examine the individual and joint effects of ambient PM_2.5 exposures and MPBMI on the risk of COWO.

Methods

We estimated exposures to ambient PM_2.5in utero and during the first 2 y of life (F2YL), using data from the U.S. Environmental Protection Agency’s (EPA’s) Air Quality System matched to residential address, in 1,446 mothe

SUBMITTER: Mao G 

PROVIDER: S-EPMC5743454 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature