Associations of Prenatal Urinary Bisphenol A Concentrations with Child Behaviors and Cognitive Abilities.

ABSTRACT:

Background

Prenatal bisphenol A (BPA) exposure has been associated with adverse neurodevelopment in epidemiological studies. However, prior studies had limited statistical power to examine sex-specific effects, and few examined child cognition.

Objectives

We estimated the association between prenatal BPA exposure and child neurobehavior at 3 y of age in a prospective cohort of 812 mothers and their children.

Methods

We measured BPA concentration in urine samples collected at ∼12 wk gestation among women enrolled in a 10-city Canadian cohort study. At approximately 3 y of age, we assessed children’s cognitive abilities with the Wechsler Primary and Preschool Scale of Intelligence^TM–III (WPPSI-III) and two scales of the Behavior Rating Inventory of Executive

SUBMITTER: Braun JM 

PROVIDER: S-EPMC5743534 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature