Pesticide Exposure and Risk of Rheumatoid Arthritis among Licensed Male Pesticide Applicators in the Agricultural Health Study.

ABSTRACT:

Background

The occupation of farming has been associated with rheumatoid arthritis (RA); pesticides may account for this association, but there are few studies.

Objectives

We investigated associations between RA and use of pesticides in the Agricultural Health Study.

Methods

The study sample was drawn from male pesticide applicators enrolled in 1993–1997 who provided questionnaire data at baseline and at least once during follow-up (over a median 18 y; interquartile range 16–19). Incident RA cases (n=220), confirmed by physicians or by self-reported use of disease-modifying antirheumatic drugs, were compared with noncases (n=26,134) who did not report RA. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression, adjus

SUBMITTER: Meyer A 

PROVIDER: S-EPMC5744649 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature