Identifying Trends in Undiagnosed Diabetes in U.S. Adults by Using a Confirmatory Definition: A Cross-sectional Study.

ABSTRACT:

Background

A common belief is that one quarter to one third of all diabetes cases remain undiagnosed. However, such prevalence estimates may be overstated by epidemiologic studies that do not use confirmatory testing, as recommended by clinical diagnostic criteria.

Objective

To provide national estimates of undiagnosed diabetes by using a confirmatory testing strategy, in line with clinical practice guidelines.

Design

Cross-sectional study.

Setting

National Health and Nutrition Examination Survey results from 1988 to 1994 and 1999 to 2014.

Participants

U.S. adults aged 20 years and older.

Measurements

Confirmed undiagnosed diabetes was defined as elevated levels of fasting glucose (≥7.0 mmol/L [≥126 mg/dL]) and hemoglobin A1c (≥6.5%) in persons wi

SUBMITTER: Selvin E 

PROVIDER: S-EPMC5744859 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature