Repeat multiparametric MRI in prostate cancer patients on active surveillance.

ABSTRACT:

Introduction

This study was conducted to describe the changes in repeat multiparametric MRI (mpMRI) occurring in prostate cancer (PCa) patients during active surveillance (AS), and to study possible associations between mpMRI-related parameters in predicting prostate biopsy (Bx) Gleason score (GS) upgrading >3+3 and protocol-based treatment change (TC).

Materials and methods

The study cohort consisted of 76 AS patients with GS 3+3 PCa and at least two consecutive mpMRIs of the prostate performed between 2006-2015. Patients were followed according to the Prostate Cancer Research International Active Surveillance (PRIAS) protocol and an additional mpMRI. The primary end points were GS upgrading (GU) (>3+3) in protocol-based Bxs and protocol-based TC.

Results

Out of 76 p

SUBMITTER: Eineluoto JT 

PROVIDER: S-EPMC5744936 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature