Sex and genotype effects on nutrient-dependent fitness landscapes in Drosophila melanogaster.

ABSTRACT: The sexes perform different reproductive roles and have evolved sometimes strikingly different phenotypes. One focal point of adaptive divergence occurs in the context of diet and metabolism, and males and females of a range of species have been shown to require different nutrients to maximize their fitness. Biochemical analyses in Drosophila melanogaster have confirmed that dimorphism in dietary requirements is associated with molecular sex differences in metabolite titres. In addition, they also showed significant within-sex genetic variation in the metabolome. To date however, it is unknown whether this metabolic variation translates into differences in reproductive fitness. The answer to this question is crucial to establish whether genetic variation is selectively neutral or in

SUBMITTER: Camus MF 

PROVIDER: S-EPMC5745421 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature