An analytical framework to derive the expected precision of genomic selection.

ABSTRACT:

Background

Formulae to predict the precision or accuracy of genomic estimated breeding values (GEBV) are important when modelling selection schemes. Simple versions of such formulae have been proposed in the past, based on a number of simplifying hypotheses, including absence of linkage disequilibrium and linkage between loci, a population made up of unrelated individuals, and that all genetic variability of the trait is explained by the genotyped loci. These formulae were based on approximations that were not always clear. The objective of this paper is to offer a unique framework to derive equations that predict the precision of GEBV from the size of the reference population and the heritability of and number of QTL controlling the quantitative trait.

Results

The exact for

SUBMITTER: Elsen JM 

PROVIDER: S-EPMC5745666 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature