Specific excitatory connectivity for feature integration in mouse primary visual cortex.

ABSTRACT: Local excitatory connections in mouse primary visual cortex (V1) are stronger and more prevalent between neurons that share similar functional response features. However, the details of how functional rules for local connectivity shape neuronal responses in V1 remain unknown. We hypothesised that complex responses to visual stimuli may arise as a consequence of rules for selective excitatory connectivity within the local network in the superficial layers of mouse V1. In mouse V1 many neurons respond to overlapping grating stimuli (plaid stimuli) with highly selective and facilitatory responses, which are not simply predicted by responses to single gratings presented alone. This complexity is surprising, since excitatory neurons in V1 are considered to be mainly tuned to single preferred or

SUBMITTER: Muir DR 

PROVIDER: S-EPMC5746254 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature