Instant Construction and Visualization of Crowded Biological Environments.

ABSTRACT: We present the first approach to integrative structural modeling of the biological mesoscale within an interactive visual environment. These complex models can comprise up to millions of molecules with defined atomic structures, locations, and interactions. Their construction has previously been attempted only within a non-visual and non-interactive environment. Our solution unites the modeling and visualization aspect, enabling interactive construction of atomic resolution mesoscale models of large portions of a cell. We present a novel set of GPU algorithms that build the basis for the rapid construction of complex biological structures. These structures consist of multiple membrane-enclosed compartments including both soluble molecules and fibrous structures. The compartments are define

SUBMITTER: Klein T 

PROVIDER: S-EPMC5746312 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature