The acute toxicity of major ion salts to Ceriodaphnia dubia. III. Mathematical models for mixture toxicity.

ABSTRACT: Based on previous research on the acute toxicity of major ions (Na⁺ , K⁺ , Ca²⁺ , Mg²⁺ , Cl^- , SO₄^2- , and HCO₃^- /CO₃^2- ) to Ceriodaphnia dubia, a mathematical model was developed for predicting the median lethal concentration (LC50) for any ion mixture, excepting those dominated by K-specific toxicity. One component of the model describes a mechanism of general ion toxicity to which all ions contribute and predicts LC50s as a function of osmolarity and Ca activity. The other component describes Mg/Ca-specific toxicity to apply when such toxicity exceeds the general ion toxicity and predicts LC50s as a function of Mg and Ca activities. This model not only tracks well the

SUBMITTER: Erickson RJ 

PROVIDER: S-EPMC5747266 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature