Development of a core outcome set for studies involving patients undergoing major lower limb amputation for peripheral arterial disease: study protocol for a systematic review and identification of a core outcome set using a Delphi survey.

ABSTRACT:

Background

The development of a standardised reporting set is important to ensure that research is directed towards the most important outcomes and that data is comparable. To ensure validity, the set must be agreed by a consensus of stakeholders including patients, healthcare professionals and lay representatives. There is currently no agreed core outcome set for patients undergoing major lower limb amputation for peripheral arterial disease (PAD) for either short- or medium-term research outcomes. By developing these sets we aim to rationalise future trial outcomes, facilitate meta-analysis and improve the quality and applicability of amputation research.

Methods/design

We will undertake a comprehensive systematic review of studies of patients undergoing major lower limb a

SUBMITTER: Ambler GK 

PROVIDER: S-EPMC5747272 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature