Is Body Mass Index the Best Adiposity Measure for Prostate Cancer Risk? Results From a Veterans Affairs Biopsy Cohort.

ABSTRACT:

Objective

To test multiple adiposity measures and prostate cancer (PC) risk in men undergoing prostate biopsy. We hypothesized that body mass index (BMI), body fat, and waist circumference would be highly correlated, and all would be associated with aggressive PC, but not overall risk.

Subjects and methods

A case (483)-control (496) study among men undergoing prostate biopsy from 2007 to 2016 was conducted at the Durham Veterans Affairs Medical Center. Anthropometric and self-reported measurements were taken. Percent body fat was measured. Associations between adiposity measures and PC risk and high-grade PC (Gleason ≥7) were examined using logistic regression.

Results

BMI, percent body fat, and waist circumference were highly correlated (ρ ≥ .79) (P < .001). On multi

SUBMITTER: Guerrios-Rivera L 

PROVIDER: S-EPMC5747369 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature