A diagnostic and epidemiologic investigation of acute febrile illness (AFI) in Kilombero, Tanzania.

ABSTRACT:

Introduction

In low-resource settings, empiric case management of febrile illness is routine as a result of limited access to laboratory diagnostics. The use of comprehensive fever syndromic surveillance, with enhanced clinical microbiology, advanced diagnostics and more robust epidemiologic investigation, could enable healthcare providers to offer a differential diagnosis of fever syndrome and more appropriate care and treatment.

Methods

We conducted a year-long exploratory study of fever syndrome among patients ≥ 1 year if age, presenting to clinical settings with an axillary temperature of ≥37.5°C and symptomatic onset of ≤5 days. Blood and naso-pharyngeal/oral-pharyngeal (NP/OP) specimens were collected and analyzed, respectively, using AFI and respiratory TaqMan Array C

SUBMITTER: Hercik C 

PROVIDER: S-EPMC5747442 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature