Variance components associated with long-echo-time MR spectroscopic imaging in human brain at 1.5T and 3T.

ABSTRACT:

Object

Magnetic resonance spectroscopic imaging (MRSI) is increasingly used in medicine and clinical research. Previous reliability studies have used small samples and focussed on limited aspects of variability; information regarding 1.5T versus 3T performance is lacking. The aim of the present work was to measure the inter-session, intra-session, inter-subject, within-brain and residual variance components using both 1.5T and 3T MR scanners.

Materials and methods

Eleven healthy volunteers were invited for MRSI scanning on three occasions at both 1.5T and 3T, with four scans acquired at each visit. We measured variance components, correcting for grey matter and white matter content of voxels, of metabolite peak areas and peak area ratios.

Results

Residual variance was

SUBMITTER: Thrippleton MJ 

PROVIDER: S-EPMC5747450 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature