Exposure to traffic-related air pollution and the composition of the gut microbiota in overweight and obese adolescents.

ABSTRACT:

Background

Traffic-related air pollution (TRAP) exposure has been linked to type 2 diabetes and metabolic dysfunction in humans. Animal studies suggest that air pollutants may alter the composition of the gut microbiota, which may negatively impact metabolic health through changes in the composition and/or function of the gut microbiome.

Objectives

The primary aim of this study was to determine whether elevated TRAP exposure was correlated with gut bacterial taxa in overweight and obese adolescents from the Meta-AIR (Metabolic and Asthma Incidence Research) study. The secondary aim was to examine whether gut microbial taxa correlated with TRAP were also correlated with risk factors for type 2 diabetes (e.g., fasting glucose levels). We additionally explored whether correlati

SUBMITTER: Alderete TL 

PROVIDER: S-EPMC5747978 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature