Multi-Omic Biogeography of the Gastrointestinal Microbiota of a Pre-Weaned Lamb.

ABSTRACT: The digestive functions of the pre-weaned lamb gastrointestinal tracts (GITs) have been the subject of much research in recent years, but the microbial and host functions underlying these complex processes remain largely unknown. Here, we undertook a proof-of-principle metaproteogenomic investigation on luminal and mucosal samples collected from 10 GITs of a 30-day-old pre-weaned lamb. We demonstrate that the analysis of the diverse ecological niches along the GITs can reveal microbiota composition and metabolic functions, although low amounts of microbial proteins could be identified in the small intestinal and mucosal samples. Our data suggest that a 30-day lamb has already developed mature microbial functions in the forestomachs, while the effect of the milky diet appears to be more evi

SUBMITTER: Palomba A 

PROVIDER: S-EPMC5748571 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature