Deciphering the Relationship between Obesity and Various Diseases from a Network Perspective.

ABSTRACT: The number of obesity cases is rapidly increasing in developed and developing countries, thereby causing significant health problems worldwide. The pathologic factors of obesity at the molecular level are not fully characterized, although the imbalance between energy intake and consumption is widely recognized as the main reason for fat accumulation. Previous studies reported that obesity can be caused by the dysfunction of genes associated with other diseases, such as myocardial infarction, hence providing new insights into dissecting the pathogenesis of obesity by investigating its associations with other diseases. In this study, we investigated the relationship between obesity and diseases from Online Mendelian Inheritance in Man (OMIM) databases on the protein-protein interaction (PPI)

SUBMITTER: Chen L 

PROVIDER: S-EPMC5748710 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature