Effects of high alcohol intake, alcohol-related symptoms and smoking on mortality.

ABSTRACT:

Background and aims

Both high alcohol intake and alcohol dependence increase mortality, and both are associated with smoking. We aimed to compare the associations of quantity of alcohol, number of alcohol-related symptoms and smoking history with all-cause mortality, and to assess symptom count and smoking history as confounders or mediators of the effects of high alcohol intake.

Design

Survival was analysed by Cox regression with sex, body mass index, alcohol intake (overall and by beverage), maximum drinks on any day, alcohol symptom count and smoking status as potential predictors of age at death.

Setting

Australia.

Participants

Participants were apparently healthy volunteers consisting of 33 593 Australian adult twins and their relatives who completed quest

SUBMITTER: Whitfield JB 

PROVIDER: S-EPMC5749262 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature