Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation.

ABSTRACT:

Background

We tested the hypothesis that routine MRI would improve the care and well-being of preterm infants and their families.

Design

Parallel-group randomised trial (1.1 allocation; intention-to-treat) with nested diagnostic and cost evaluations (EudraCT 2009-011602-42).

Setting

Participants from 14 London hospitals, imaged at a single centre.

Patients

511 infants born before 33 weeks gestation underwent both MRI and ultrasound around term. 255 were randomly allocated (siblings together) to receive only MRI results and 255 only ultrasound from a paediatrician unaware of unallocated results; one withdrew before allocation.

Main outcome measures

Maternal anxiety, measured by the State-Trait Anxiety inventory (STAI) assessed in 206/214 mothers receiving

SUBMITTER: Edwards AD 

PROVIDER: S-EPMC5750369 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature