Differences in carbon source usage by dental plaque in children with and without early childhood caries.

ABSTRACT: Early childhood caries (ECC) is a considerable pediatric and public health problem worldwide. Preceding studies have focused primarily on bacterial diversity at the taxonomic level. Although these studies have provided significant information regarding the connection between dental caries and oral microbiomes, further comprehension of this microbial community's ecological relevance is limited. This study identified the carbon source metabolic differences in dental plaque between children with and without ECC. We compared the microbial community functional diversity in 18 caries-free subjects with 18 severe ECC patients based on sole carbon source usage using a Biolog assay. The anaerobic microbial community in the ECC patients displayed greater metabolic activity than that of the control g

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC5750455 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature