Direct Bilirubin Levels and Risk of Metabolic Syndrome in Healthy Chinese Men.

ABSTRACT:

Background

Serum bilirubin is a potent endogenous antioxidant with anti-inflammatory properties. Several cross-sectional studies have reported that bilirubin was negatively associated with metabolic syndrome. However, in recent longitudinal studies, the relations between bilirubin and metabolic syndrome are inconsistent. Moreover, previous studies mainly focused on serum total bilirubin which is the sum of direct bilirubin and indirect bilirubin. For these reasons, the longitudinal effect of bilirubin subtypes on incident metabolic syndrome was evaluated in Chinese men.

Methods

The study cohort involved 1339 Chinese men without metabolic syndrome. Metabolic syndrome was defined by the American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) criteria, u

SUBMITTER: Li XH 

PROVIDER: S-EPMC5750483 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature