Personalised fluid resuscitation in the ICU: still a fluid concept?

ABSTRACT: The administration of intravenous fluid to critically ill patients is one of the most common, but also one of the most fiercely debated, interventions in intensive care medicine. Even though many thousands of patients have been enrolled in large trials of alternative fluid strategies, consensus remains elusive and practice is widely variable. Critically ill patients are significantly heterogeneous, making a one size fits all approach unlikely to be successful.New data from basic, animal, and clinical research suggest that fluid resuscitation could be associated with significant harm. There are several important limitations and concerns regarding fluid bolus therapy as it is currently being used in clinical practice. These include, but are not limited to: the lack of an agreed definition; l

SUBMITTER: van Haren F 

PROVIDER: S-EPMC5751583 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature