Plasticity of the Pyruvate Node Modulates Hydrogen Peroxide Production and Acid Tolerance in Multiple Oral Streptococci.

ABSTRACT: Commensal Streptococcus sanguinis and Streptococcus gordonii are pioneer oral biofilm colonizers. Characteristic for both is the SpxB-dependent production of H₂O₂, which is crucial for inhibiting competing biofilm members, especially the cariogenic species Streptococcus mutans H₂O₂ production is strongly affected by environmental conditions, but few mechanisms are known. Dental plaque pH is one of the key parameters dictating dental plaque ecology and ultimately oral health status. Therefore, the objective of the current study was to characterize the effects of environmental pH on H₂O₂ production by S. sanguinis and S. gordoniiS. sanguinis H₂O₂ production was no

SUBMITTER: Cheng X 

PROVIDER: S-EPMC5752870 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature