NPASS: natural product activity and species source database for natural product research, discovery and tool development.

ABSTRACT: There has been renewed interests in the exploration of natural products (NPs) for drug discovery, and continuous investigations of the therapeutic claims and mechanisms of traditional and herbal medicines. In-silico methods have been employed for facilitating these studies. These studies and the optimization of in-silico algorithms for NP applications can be facilitated by the quantitative activity and species source data of the NPs. A number of databases collectively provide the structural and other information of ∼470 000 NPs, including qualitative activity information for many NPs, but only ∼4000 NPs are with the experimental activity values. There is a need for the activity and species source data of more NPs. We therefore developed a new database, NPASS (Natural Product Activity and S

SUBMITTER: Zeng X 

PROVIDER: S-EPMC5753227 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature