FusionDB: assessing microbial diversity and environmental preferences via functional similarity networks.

ABSTRACT: Microbial functional diversification is driven by environmental factors, i.e. microorganisms inhabiting the same environmental niche tend to be more functionally similar than those from different environments. In some cases, even closely phylogenetically related microbes differ more across environments than across taxa. While microbial similarities are often reported in terms of taxonomic relationships, no existing databases directly link microbial functions to the environment. We previously developed a method for comparing microbial functional similarities on the basis of proteins translated from their sequenced genomes. Here, we describe fusionDB, a novel database that uses our functional data to represent 1374 taxonomically distinct bacteria annotated with available metadata: habitat/ni

SUBMITTER: Zhu C 

PROVIDER: S-EPMC5753390 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature