No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes.

ABSTRACT:

Background

Studies investigating associations between ACTN3 R577X and ACE I/D genotypes and endurance athletic status have been limited by small sample sizes from mixed sport disciplines and lack quantitative measures of performance.

Aim

To examine the association between ACTN3 R577X and ACE I/D genotypes and best personal running times in a large homogeneous cohort of endurance runners.

Methods

We collected a total of 1064 personal best 1500, 3000, 5000 m and marathon running times of 698 male and female Caucasian endurance athletes from six countries (Australia, Greece, Italy, Poland, Russia and UK). Athletes were genotyped for ACTN3 R577X and ACE ID variants.

Results

There was no association between ACTN3 R577X or ACE I/D genotype and running performance at

SUBMITTER: Papadimitriou ID 

PROVIDER: S-EPMC5753575 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature