Radiation-Induced DNA Damage in Operators Performing Endovascular Aortic Repair.

ABSTRACT:

Background

Radiation exposure during fluoroscopically guided interventions such as endovascular aortic repair (EVAR) is a growing concern for operators. This study aimed to measure DNA damage/repair markers in operators perfoming EVAR.

Methods

Expression of the DNA damage/repair marker, γ-H2AX and DNA damage response marker, phosphorylated ataxia telangiectasia mutated (pATM), were quantified in circulating lymphocytes in operators during the peri-operative period of endovascular (infrarenal, branched, and fenestrated) and open aortic repair using flow cytometry. These markers were separately measured in the same operators but this time wearing leg lead shielding in addition to upper body protection and compared with those operating with unprotected legs. Susceptibility to r

SUBMITTER: El-Sayed T 

PROVIDER: S-EPMC5753831 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature