Dataset Information
Spectroscopic and crystallographic characterization of two cathinone derivatives: 1-(4-fluorophenyl)-2-(methylamino)pentan-1-one (4-FPD) hydrochloride and 1-(4-methylphenyl)-2-(ethylamino)pentan-1-one (4-MEAP) hydrochloride.
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ABSTRACT: Purpose
In this study, we performed identification and physicochemical characterization of two cathinone derivatives, 4-FPD and 4-MEAP, found in market-available materials.Methods
The compounds were characterized by electrospray ionization ion trap mass spectrometry (MS) in MS2 and MS3 modes, gas chromatography-MS, infrared, Raman and ultraviolet-visible spectroscopies, X-ray crystallography, differential scanning calorimetry and nuclear magnetic resonance spectroscopy.Results
We could obtain detailed and comprehensive physicochemical characterization of 4-FPD and 4-MEAP-new cathinone derivatives available on the designer drugs market.Conclusions
Dynamic growth in the number of psychoactive substances available on the designer drug markets makes it compulsory to obtain analytical data allowing unequivocal identification of these drugs in the fastest possible way. In this study we presented analytical data useful in quick identification of the investigated compounds.
SUBMITTER: Rojkiewicz M
PROVIDER: S-EPMC5754380 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Spectroscopic and crystallographic characterization of two cathinone derivatives: 1-(4-fluorophenyl)-2-(methylamino)pentan-1-one (4-FPD) hydrochloride and 1-(4-methylphenyl)-2-(ethylamino)pentan-1-one (4-MEAP) hydrochloride.
Forensic toxicology 20171117 1
<h4>Purpose</h4>In this study, we performed identification and physicochemical characterization of two cathinone derivatives, 4-FPD and 4-MEAP, found in market-available materials.<h4>Methods</h4>The compounds were characterized by electrospray ionization ion trap mass spectrometry (MS) in MS<sup>2</sup> and MS<sup>3</sup> modes, gas chromatography-MS, infrared, Raman and ultraviolet-visible spectroscopies, X-ray crystallography, differential scanning calorimetry and nuclear magnetic resonance s ...[more]