Estimation on local transmission of malaria by serological approach under low transmission setting in Myanmar.

ABSTRACT:

Background

As the prevalence of the malaria has been decreasing in many endemic countries including Myanmar, malaria elimination in Greater Mekong Region was targeted not later than 2030. The relevance of molecular and serological tools to identify residual transmission remains to be established in this setting.

Methods

One-year cohort study was conducted and sera samples were collected in every 3 months with active and passive case detection for clinical malaria episodes by RDT, microscopy and molecular method. The sera were used to detect the malaria antibody against PfMSP1-19, PvAMA1, PvDBPII and PvMSP1-19 by protein microarray.

Results

Among the recruited 1182 participants, there was no RDT positive case for malaria infection although two vivax infections were det

SUBMITTER: Nyunt MH 

PROVIDER: S-EPMC5755288 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature