Cardiovascular Events in a Physical Activity Intervention Compared With a Successful Aging Intervention: The LIFE Study Randomized Trial.

ABSTRACT:

Importance

Whether sustained physical activity prevents cardiovascular disease (CVD) events in older adults is uncertain.

Objective

To test the hypothesis that cardiovascular morbidity and mortality would be reduced in participants in a long-term physical activity program.

Design, setting, and participants

The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, randomized trial. Participants were recruited at 8 centers in the United States. We randomized 1635 sedentary men and women aged 70 to 89 years with a Short Physical Performance Battery (SPPB) score of 9 or less but able to walk 400 m.

Interventions

The physcial activity (PA) intervention was a structured moderate-intensity program, predominantly walking 2 times per week o

SUBMITTER: Newman AB 

PROVIDER: S-EPMC5755709 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature