Absolute lung size and the sex difference in breathlessness in the general population.

ABSTRACT:

Background

Breathlessness is associated with major adverse health outcomes and is twice as common in women as men in the general population. We evaluated whether this is related to their lower absolute lung volumes.

Methods

Cross-sectional analysis of the population-based Swedish CardioPulmonarybioImage Study (SCAPIS) Pilot, including static spirometry and diffusing capacity (n = 1,013; 49% women). Breathlessness was measured using the modified Medical Research Council (mMRC) scale and analyzed using ordinal logistic regression adjusting for age, pack-years of smoking, body mass index, chronic airway limitation, asthma, chronic bronchitis, depression and anxiety in all models.

Results

Breathlessness was twice as common in women as in men; adjusted odds ratio (OR) 2.20

SUBMITTER: Ekstrom M 

PROVIDER: S-EPMC5755925 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature