Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades.

ABSTRACT:

Objectives

The purpose of this study was to describe the temporal trends in prevalence of left ventricular systolic dysfunction (LVSD) in individuals without and with heart failure (HF) in the community over a 3-decade period of observation.

Background

Temporal trends in the prevalence and management of major risk factors may affect the epidemiology of HF.

Methods

We compared the frequency, correlates, and prognosis of LVSD (left ventricular ejection fraction [LVEF] <50%) among Framingham Study participants without and with clinical HF in 3 decades (1985 to 1994, 1995 to 2004, and 2005 to 2014).

Results

Among participants without HF (12,857 person-observations, mean age 53 years, 56% women), the prevalence of LVSD on echocardiography decreased (3.38% in 1985 to

SUBMITTER: Vasan RS 

PROVIDER: S-EPMC5756128 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature