Papain-like cysteine proteases in Carica papaya: lineage-specific gene duplication and expansion.

ABSTRACT:

Background

Papain-like cysteine proteases (PLCPs), a large group of cysteine proteases structurally related to papain, play important roles in plant development, senescence, and defense responses. Papain, the first cysteine protease whose structure was determined by X-ray crystallography, plays a crucial role in protecting papaya from herbivorous insects. Except the four major PLCPs purified and characterized in papaya latex, the rest of the PLCPs in papaya genome are largely unknown.

Results

We identified 33 PLCP genes in papaya genome. Phylogenetic analysis clearly separated plant PLCP genes into nine subfamilies. PLCP genes are not equally distributed among the nine subfamilies and the number of PLCPs in each subfamily does not increase or decrease proportionally among th

SUBMITTER: Liu J 

PROVIDER: S-EPMC5756445 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature