Advances in the Studies of Ginkgo Biloba Leaves Extract on Aging-Related Diseases.

ABSTRACT: The prevalence of degenerative disorders in public health has promoted in-depth investigations of the underlying pathogenesis and the development of new treatment drugs. Ginkgo biloba leaves extract (EGb) is obtained from Ginkgo biloba leaves and has been used for thousands of years. In recent decades, both basic and clinical studies have established the effects of EGb. It is widely used in various degenerative diseases such as cerebrovascular disease, Alzheimer's disease, macroangiopathy and more. Here, we reviewed several pharmacological mechanisms of EGb, including its antioxidant properties, prevention of mitochondrial dysfunctions, and effect on apoptosis. We also described some clinical applications of EGb, such as its effect on neuro and cardiovascular protection, and anticancer pro

SUBMITTER: Zuo W 

PROVIDER: S-EPMC5758353 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature