Home Exercise Training Improves Exercise Capacity in Cirrhosis Patients: Role of Exercise Adherence.

ABSTRACT: Cirrhosis patients have reduced peak aerobic power (peak VO₂) that is associated with reduced survival. Supervised exercise training increases exercise tolerance. The effect of home-based exercise training (HET) in cirrhosis is unknown. The objective was to evaluate the safety and efficacy of 8 weeks of HET on peak VO₂, 6-minute walk distance (6MWD), muscle mass, and quality of life in cirrhosis. Random assignment to 8 weeks of HET (moderate to high intensity cycling exercise, 3 days/week) or usual care. Exercise adherence defined as completing ≥80% training sessions. Paired t-tests and analysis of covariance used for comparisons. Forty patients enrolled: 58% male, mean age 57 y, 70% Child Pugh-A. Between group increases in peak VO₂ (1.7, 95% CI: -0.33 to 3

SUBMITTER: Kruger C 

PROVIDER: S-EPMC5758716 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature