Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant.

ABSTRACT: Selenium is an essential mineral naturally found in soil, water, and some of the food. As an antioxidant, it is one of the necessary trace elements in human body and has been suggested as a dietary supplement for health benefit. Although the human body only needs a trace amount of selenium every day, plenty of recent studies have revealed that selenium is indispensable for maintaining normal functions of metabolism. In this study, we reviewed the antioxidant role of nutritional supplementation of selenium in the management of major chronic metabolic disorders, including hyperlipidaemia, hyperglycaemia, and hyperphenylalaninemia. Clinical significance of selenium deficiency in chronic metabolic diseases was elaborated, while clinical and experimental observations of dietary supplementation

SUBMITTER: Wang N 

PROVIDER: S-EPMC5758946 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature