Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families.

ABSTRACT:

Background and aims

Parental alcohol use disorders (AUDs) and parental separation are associated with increased risk for early use of alcohol in offspring, but whether they increase risks for early use of other substances and for early sexual debut is under-studied. We focused on associations of parental AUDs and parental separation with substance initiation and sexual debut to (1) test the strength of the associations of parental AUDs and parental separation with time to initiation (age in years) of alcohol, tobacco and cannabis use and sexual debut and (2) compare the strength of association of parental AUD and parental separation with initiation.

Design

Prospective adolescent and young adult cohort of a high-risk family study, the Collaborative Study on the Genetics of Al

SUBMITTER: McCutcheon VV 

PROVIDER: S-EPMC5760304 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature