Associations between adolescent cannabis use and neuropsychological decline: a longitudinal co-twin control study.

ABSTRACT:

Aims

This study tested whether adolescents who used cannabis or met criteria for cannabis dependence showed neuropsychological impairment prior to cannabis initiation and neuropsychological decline from before to after cannabis initiation.

Design

A longitudinal co-twin control study.

Setting and participants

Participants were 1989 twins from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of twins born in England and Wales from 1994 to 1995.

Measurements

Frequency of cannabis use and cannabis dependence were assessed at age 18. Intelligence quotient (IQ) was obtained at ages 5, 12 and 18. Executive functions were assessed at age 18.

Findings

Compared with adolescents who did not use cannabis, adolescents

SUBMITTER: Meier MH 

PROVIDER: S-EPMC5760333 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature