Ontology highlight
ABSTRACT:
SUBMITTER: Thomas S
PROVIDER: S-EPMC5761219 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Journal of pharmaceutical analysis 20130824 5
A new impurity was detected during high performance liquid chromatographic (HPLC) analysis of eslicarbazepine acetate active pharmaceutical ingredient. The structure of unknown impurity was postulated based on liquid chromatography mass spectrometry using electrospray ionization and ion trap analyzer (LC/ESI-IT/MS) analysis. Proposed structure of impurity was unambiguously confirmed by synthesis followed by characterization using <sup>1</sup>H, <sup>13</sup>C nuclear magnetic resonance spectrome ...[more]