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Trabecular Bone Morphology Correlates With Skeletal Maturity and Body Composition in Healthy Adolescent Girls.


ABSTRACT: Context:Growth in healthy children is associated with changes in bone density and microarchitecture. Trabecular morphology is an additional important determinant of bone strength, but little is currently known about trabecular morphology in healthy young people. Objective:To investigate associations of trabecular morphology with increasing maturity and with body composition in healthy girls. Design:Cross-sectional study. Setting:Academic research center. Participants:Eighty-six healthy girls aged 9 to 18 years. Main Outcome Measures:High-resolution peripheral quantitative computed tomography and individual trabecula segmentation were used to assess volumetric bone density, microarchitecture, and trabecular morphology (plate-like vs rod-like) at the distal radius and tibia. Results:Plate-li

SUBMITTER: Mitchell DM 

PROVIDER: S-EPMC5761494 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature