Occupational exposure to chlorinated solvents and kidney cancer: a case-control study.

ABSTRACT:

Objectives

Trichloroethylene, a chlorinated solvent widely used for metal degreasing, is classified by the International Agency for Research on Cancer as a kidney carcinogen. Other chlorinated solvents are suspected carcinogens, most notably the cleaning solvent perchloroethylene, although it is unclear whether they are associated with kidney cancer. We investigated kidney cancer associations with occupational exposure to 6 chlorinated solvents (trichloroethylene, perchloroethylene, 1,1,1-trichloroethane, carbon tetrachloride, chloroform, and methylene chloride) within a case-control study using detailed exposure assessment methods.

Methods

Cases (n=1217) and controls (n=1235) provided information on their occupational histories and, for selected occupations, on tasks involv

SUBMITTER: Purdue MP 

PROVIDER: S-EPMC5761658 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature