The global problem of childhood diarrhoeal diseases: emerging strategies in prevention and management.

ABSTRACT: Acute diarrhoeal diseases remain a leading cause of global morbidity and mortality particularly among young children in resource-limited countries. Recent large studies utilizing case-control design, prospective sampling and more sensitive and broad diagnostic techniques have shed light on particular pathogens of importance and highlighted the previously under recognized impact of these infections on post-acute illness mortality and growth. Vaccination, particularly against rotavirus, has emerged as a key effective means of preventing significant morbidity and mortality from childhood diarrhoeal disease. Other candidate vaccines against leading diarrhoeal pathogens, such as enterotoxigenic Escherichia coli and Shigella spp., also hold significant promise in further ameliorati

SUBMITTER: Mokomane M 

PROVIDER: S-EPMC5761924 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature