Ultra-short-course booster is effective in recurrent grass pollen-induced allergic rhinoconjunctivitis.

ABSTRACT:

Background

A relevant proportion of allergic rhinoconjunctivitis (ARC) patients experience recurrent symptoms after successfully completing allergen immunotherapy (AIT). This prospective, controlled, noninterventional study used internationally standardized instruments to determine the clinical effects of a preseasonal, ultra-short-course booster AIT on clinical outcome parameters.

Methods

This two-arm study included patients aged ≥12 years with recurrent grass pollen-induced seasonal AR who had completed a successful course of any grass pollen AIT at least 5 years before enrolment. Overall, 56 patients received one preseasonal short-course booster AIT using tyrosine-absorbed grass pollen allergoids containing the adjuvant monophosphoryl lipid A (MPL^® ); 51 contro

SUBMITTER: Pfaar O 

PROVIDER: S-EPMC5763416 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature