Resounding failure to replicate links between developmental language disorder and cerebral lateralisation.

ABSTRACT:

Background

It has been suggested that failure to establish cerebral lateralisation may be related to developmental language disorder (DLD). There has been weak support for any link with handedness, but more consistent reports of associations with functional brain lateralisation for language. The consistency of lateralisation across different functions may also be important. We aimed to replicate previous findings of an association between DLD and reduced laterality on a quantitative measure of hand preference (reaching across the midline) and on language laterality assessed using functional transcranial Doppler ultrasound (fTCD).

Methods

From a sample of twin children aged from 6;0 to 11;11 years, we identified 107 cases of DLD and 156 typically-developing comparison cases f

SUBMITTER: Wilson AC 

PROVIDER: S-EPMC5764032 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature