Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering.

ABSTRACT: A two-color vibrational imaging technique for simultaneously mapping glucose uptake and incorporation activity inside single living cells is reported. Heterogeneous patterns of glucose metabolism are directly visualized from the ratiometric two-color images for various cell types, cells undergoing epithelia-to-mesenchymal transitions and live mouse brain tissues. The two-color imaging of glucose metabolism here demonstrates the development of multi-functional vibrational probes for multicolor imaging of cellular metabolism.

SUBMITTER: Long R 

PROVIDER: S-EPMC5764084 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature